Journal of Korean Medicine Rehabilitation : eISSN 2288-4114 / pISSN 1229-1854

Fig. 14.

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Fig. 14. Effect of HWJ on mRNA level of RANKL in bone callus from mouse tibia on 7, 14, and 21 days postfracture. BMDMs were isolated from non-fractured, fractured and fractured with HWJ-administered mouse tibia at different time points (7, 14 and 21 days postfracture) and used for total RNA extraction. Prepared RNA was used for measuring the expression of mRNA of RANKL. NF: without bone fracture group, CON: only bone fracture group, HWJ 50: bone fracture with HWJ 50 mg/kg treated group, HWJ 100: bone fracture with HWJ 100 mg/kg treated group. HWJ: Hwaweo-Jeon, RANKL: receptor activator of nuclear factor kappa-B ligand, BMDMs: bone marrow-derived macrophage. ***p<0.001 versus CON group.
J Korean Med Rehabi 2020;30:13-29 https://doi.org/10.18325/jkmr.2020.30.1.13
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