Fig. 3. The results of liver mRNA expression by quantitative polymerase chain reaction and histopathological findings of liver tissue in each group. (A) Genes analyzed from liver tissue are related to gluconeogenesis, lipogenesis, and inflammation. (B~D) Samples were done by hematoxylin and eosin staining and white circles manifest the lipid droplets (×200); These are (B) the result of NC group, (C) HFD group, and (D) BIT group. (E~G) Samples were done by Oil Red O staining and the red sites manifest the distribution of lipid (×400); These are (E) the result of NC group, (F) HFD group, and (G) BIT group. All data represents standard error of mean. NC: normal control, HFD: high-fat diet, BIT: Baekhogainsam-tang, PEPCK: phosphoenolpyruvate carboxykinase, GLUT2: glucose transporter type 2, G6Pase: glucose-6-phosphatase, LPL: lipoprotein lipase, PPAR-γ: peroxisome proliferator-activated receptor γ, ACC1: acetyl-CoA carboxylase 1, TNF-α: tumor necrosis factor-α, MCP-1: monocyte chemoattractant protein-1. ^#p<0.05, ^##p<0.01 (#: vs. NC). ^*p<0.05, ^**p<0.01 (*: vs. HFD).

J Korean Med Rehabi 2023;33:1-15 https://doi.org/10.18325/jkmr.2023.33.3.1

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