Fig. 6. The results of large intestine mRNA expression by quantitative polymerase chain reaction and histopathological findings of large intestine tissue in each group. (A) Genes are related to gut permeability and inflammation. (B~D) The large intestine tissue was stained with periodic acid-Schiff staining (×400). The villi of the intestine was stained purple; (B) It is the intestinal state of NC group, (C) HFD group, and (D) BIT group. All data represents standard error of mean. NC: normal control, HFD: high-fat diet, BIT: Baekhogainsam-tang, ZO-1: zonula occludens-1, IL-1β: interleukin-1 beta, MCP-1: monocyte chemoattractant protein-1, TLR2: toll-like receptor 2. ^#p<0.05, ^##p<0.01, ^####p<0.0001 (#: vs. NC). ^**p<0.01, ^***p<0.001, ^****p<0.0001 (*: vs. HFD).

J Korean Med Rehabi 2023;33:1-15 https://doi.org/10.18325/jkmr.2023.33.3.1

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