Fig. 4. Histological observation on joint (H&E, ×100). The knee joint was evaluated histologically to determine cartilage damage using H&E. The control group exhibited histological changes like irregular cartilage surface and cartilage degeneration. Besides, Euiiin-tang water extract (EIIT) treatment improved such histological features. Normal: normal rats that did not induce osteoarthritis, Control: monosodium iodoacetate (MIA)-induced and distilled water administrated osteoarthritis rats, INDO: MIA-induced and indomethacin 5 mg/kg administrated osteoarthritis rats, EIIT100: MIA-induced and Euiiin-tang 100 mg/kg administrated osteoarthritis rats, EIIT200: MIA-induced and Euiiin-tang 200 mg/kg administrated osteoarthritis rats.

J Korean Med Rehabi 2023;33:17-32 https://doi.org/10.18325/jkmr.2023.33.3.17

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