Fig. 5. Histological observation on joint (Safranin-O staining, ×100). The knee joint was evaluated histologically to determine cartilage damage using Safranin-O staining. The control group showed severe proteoglycan loss. Besides, Euiiin-tang water extract (EIIT) treatment improved such histological feature. Normal: normal rats that did not induce osteoarthritis, Control: monosodium iodoacetate (MIA)-induced and distilled water administrated osteoarthritis rats, INDO: MIA-induced and indomethacin 5 mg/kg administrated osteoarthritis rats, EIIT100: MIA-induced and Euiiin-tang 100 mg/kg administrated osteoarthritis rats, EIIT200: MIA-induced and Euiiin-tang 200 mg/kg administrated osteoarthritis rats.

J Korean Med Rehabi 2023;33:17-32 https://doi.org/10.18325/jkmr.2023.33.3.17

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