A Literature Review of Effectiveness on the Gongjin-dan (Gongchen-dan)
Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Won-Kwang University, Medical Research Division, Korea Institute of Oriental Medicine*, Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Woo-Suk University†
Correspondence to: Jung-Han Lee,
Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Won-Kwang University, 460, Iksan-daero, Iksan 570-749, Korea
TEL (063) 859-2807
FAX (063) 841-0033
E-mail milpaso@wku.ac.kr
Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Won-Kwang University, 460, Iksan-daero, Iksan 570-749, Korea
TEL (063) 859-2807
FAX (063) 841-0033
E-mail milpaso@wku.ac.kr
Received: June 25, 2013; Revised: July 6, 2013; Accepted: July 8, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Abstract
- Objectives The purpose of this study was to investigate the effectiveness of the Gongjin-dan (Gongchen-dan, here in after GJD) in order to obtain the evidence for clinical application.
Methods The GJD-related articles published from 1990 to 2013 were searched using “Korean Traditional Knowledge Portal”, “Oriental Medicine Advanced Searching Integrated System (OASIS)”, “Korean Association of Medical Journal Edition (Koreamed)”, “Research Information Services (RISS4U)”, “Korean Medicine Database (KMbase)”, “National Discovery for Science Leader (NDSL)”, “PubMed”, “China National Knowledge Infrastructure (CNKI)”. The search keywords were “Gongjin-dan”, “Gongchen-dan”. Thirty-nine articles were obtained. After excluding the eighteen article which did not meet inclusion criteria, finally twenty-one articles were included; five clinical articles and sixteen experimental articles.
Results In clinical studies, GJD has the various effectiveness in cardiovascular diseases, alcoholic hepatitis, mild dementia, anemia. Also experimental studies related to the GJD show a variety of effects, such as anti-oxidative activity, neuroprotective activity, hepatoprotective activity, anti-inflammatory activity, immunological activity, reproductive recovery activity with fewer side-effects.
Conclusions It has been suggested that there are various effects of GJD in treating a wide-range disease. However, in order to put GJD to use for many kinds of diseases in more reasonable ways, it is needed to publish well-design clinical trial based on the variety of results of experimental studies. - Keywords : Gongjin-dan, Gongchen-dan, Gongjindan, Gongchendan, Review
